Liver problems after Clomipramine (Clomicalm) in dogs
The FDA has received 271 reports of liver problems in dogs after Clomipramine. That is 18% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.
271Reports
18%Marked serious
3.3%Recovered
8.9%Died or euthanised
38 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Clomipramine treats separation anxiety.
Products with this ingredient include Clomicalm. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Clomipramine cause liver problems in dogs?
- 271 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 38 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Liver problems with similar medicines
- Liver problems after Gabapentin 1,228 reports · 14% of its reports
- Liver problems after Selegiline (Anipryl) 325 reports · 7.9% of its reports
- Liver problems after Fluoxetine 136 reports · 5.3% of its reports
- Liver problems after Trazodone 286 reports · 11% of its reports
All reported side effects of Clomipramine in dogs · Medicines most reported with liver problems