Elevated cholesterol (total) after Clomipramine (Clomicalm) in dogs

30 reports to the FDA describe elevated cholesterol (total) in dogs given Clomipramine. That is 2.0% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

30Reports
10%Marked serious
0.0%Recovered
3.3%Died or euthanised
–Typical onset
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How the animals did

Still unwell when reported
1 3.3%
Died
1 3.3%
Not known
28 93%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
4
4–7 years
4
8–11 years
18
12+ years
3

About this medicine

Clomipramine treats separation anxiety.

Products with this ingredient include Clomicalm. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Clomipramine cause elevated cholesterol (total) in dogs?
30 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated cholesterol (total) with similar medicines

All reported side effects of Clomipramine in dogs · Medicines most reported with elevated cholesterol (total)