Seizures after Clomipramine (Clomicalm) in dogs

79 reports to the FDA describe seizures in dogs given Clomipramine. That is 5.2% of all reports for this medicine, compared with 4.4% across reports for all dog medicines.

79Reports

28%Marked serious

8.9%Recovered

19%Died or euthanised

117 daysTypical onset

How soon it started

Same day

3 19%

1–2 days

2 13%

3–7 days

1 6.3%

1–4 weeks

2 13%

Over a month

8 50%

How the animals did

Recovered

7 8.9%

Still unwell when reported

8 10%

Died

14 18%

Euthanised

1 1.3%

Not known

49 62%

Problems reported at the same time

15 19%

14 18%

13 16%

12 15%

12 15%

7 8.9%

7 8.9%

7 8.9%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Clomipramine treats separation anxiety.

Products with this ingredient include Clomicalm. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Clomipramine cause seizures in dogs?: 79 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 117 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

Seizures after Gabapentin 634 reports · 7.0% of its reports
Seizures after Selegiline (Anipryl) 265 reports · 6.4% of its reports
Seizures after Fluoxetine 210 reports · 8.1% of its reports
Seizures after Trazodone 170 reports · 6.7% of its reports

All reported side effects of Clomipramine in dogs · Medicines most reported with seizures