Seizures after Selegiline (Anipryl) in dogs

265 reports to the FDA describe seizures in dogs given Selegiline. That is 6.4% of all reports for this medicine, compared with 4.4% across reports for all dog medicines.

265Reports

6.4%Marked serious

2.6%Recovered

21%Died or euthanised

10 daysTypical onset

How soon it started

Same day

2 11%

1–2 days

3 17%

3–7 days

4 22%

1–4 weeks

6 33%

Over a month

3 17%

How the animals did

Recovered

7 2.6%

Still unwell when reported

7 2.6%

Died

51 19%

Euthanised

4 1.5%

Not known

196 74%

Problems reported at the same time

54 20%

23 8.7%

21 7.9%

16 6.0%

14 5.3%

Didn't work as expected

14 5.3%

Loss of appetite

12 4.5%

Kidney problems

12 4.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

204

About this medicine

Selegiline treats canine cognitive dysfunction.

Products with this ingredient include Anipryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Selegiline cause seizures in dogs?: 265 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

Seizures after Gabapentin 634 reports · 7.0% of its reports
Seizures after Fluoxetine 210 reports · 8.1% of its reports
Seizures after Trazodone 170 reports · 6.7% of its reports
Seizures after Clomipramine (Clomicalm) 79 reports · 5.2% of its reports

All reported side effects of Selegiline in dogs · Medicines most reported with seizures