Death after Selegiline (Anipryl) in dogs

354 reports to the FDA describe death in dogs given Selegiline. That is 8.6% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

354Reports

4.8%Marked serious

0.0%Recovered

98%Died or euthanised

20 daysTypical onset

How soon it started

Same day

2 17%

1–2 days

0 0.0%

3–7 days

1 8.3%

1–4 weeks

4 33%

Over a month

5 42%

How the animals did

Died

334 94%

Euthanised

12 3.4%

Not known

8 2.3%

Problems reported at the same time

Vomiting

62 18%

Loss of appetite

58 16%

Didn't work as expected

57 16%

54 15%

47 13%

34 9.6%

33 9.3%

32 9.0%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

245

About this medicine

Selegiline treats canine cognitive dysfunction.

Products with this ingredient include Anipryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Selegiline cause death in dogs?: 354 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 20 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

Death after Gabapentin 1,511 reports · 17% of its reports
Death after Fluoxetine 111 reports · 4.3% of its reports
Death after Trazodone 251 reports · 9.9% of its reports
Death after Clomipramine (Clomicalm) 63 reports · 4.2% of its reports

All reported side effects of Selegiline in dogs · Medicines most reported with death