Lethargy after Selegiline (Anipryl) in dogs

333 reports to the FDA describe lethargy in dogs given Selegiline. That is 8.1% of all reports for this medicine, compared with 11% across reports for all dog medicines.

333Reports

2.1%Marked serious

1.5%Recovered

14%Died or euthanised

1 daysTypical onset

How soon it started

Same day

7 39%

1–2 days

3 17%

3–7 days

2 11%

1–4 weeks

2 11%

Over a month

4 22%

How the animals did

Recovered

5 1.5%

Still unwell when reported

8 2.4%

Died

44 13%

Euthanised

1 0.3%

Not known

275 83%

Problems reported at the same time

99 30%

71 21%

47 14%

43 13%

38 11%

37 11%

34 10%

Didn't work as expected

27 8.1%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

198

About this medicine

Selegiline treats canine cognitive dysfunction.

Products with this ingredient include Anipryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Selegiline cause lethargy in dogs?: 333 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

Lethargy after Gabapentin 1,587 reports · 18% of its reports
Lethargy after Fluoxetine 440 reports · 17% of its reports
Lethargy after Trazodone 413 reports · 16% of its reports
Lethargy after Clomipramine (Clomicalm) 405 reports · 27% of its reports

All reported side effects of Selegiline in dogs · Medicines most reported with lethargy