Seizures after Fluoxetine in dogs

The FDA has received 210 reports of seizures in dogs after Fluoxetine. That is 8.1% of all reports for this medicine, compared with 4.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

210Reports

63%Marked serious

32%Recovered

10%Died or euthanised

25 daysTypical onset

How soon it started

Same day

21 18%

1–2 days

7 6.1%

3–7 days

11 9.6%

1–4 weeks

21 18%

Over a month

54 47%

How the animals did

Recovered

64 30%

Recovered with lasting effects

4 1.9%

Still unwell when reported

40 19%

Died

12 5.7%

Euthanised

9 4.3%

Not known

81 39%

Problems reported at the same time

27 13%

24 11%

21 10%

21 10%

21 10%

20 9.5%

15 7.1%

13 6.2%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Fluoxetine treats anxiety and behaviour problems.

Questions owners ask

Can Fluoxetine cause seizures in dogs?: 210 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 25 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

Seizures after Gabapentin 634 reports · 7.0% of its reports
Seizures after Selegiline (Anipryl) 265 reports · 6.4% of its reports
Seizures after Trazodone 170 reports · 6.7% of its reports
Seizures after Clomipramine (Clomicalm) 79 reports · 5.2% of its reports

All reported side effects of Fluoxetine in dogs · Medicines most reported with seizures