Tremors after Fluoxetine in dogs

The FDA has received 244 reports of tremors in dogs after Fluoxetine. That is 9.4% of all reports for this medicine, compared with 3.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

244Reports

33%Marked serious

24%Recovered

4.5%Died or euthanised

18 daysTypical onset

How soon it started

Same day

31 24%

1–2 days

12 9.4%

3–7 days

12 9.4%

1–4 weeks

21 16%

Over a month

52 41%

How the animals did

Recovered

52 21%

Recovered with lasting effects

6 2.5%

Still unwell when reported

40 16%

Died

2 0.8%

Euthanised

9 3.7%

Not known

135 55%

Problems reported at the same time

66 27%

51 21%

41 17%

33 14%

32 13%

24 9.8%

24 9.8%

Didn't work as expected

23 9.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Fluoxetine treats anxiety and behaviour problems.

Questions owners ask

Can Fluoxetine cause tremors in dogs?: 244 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 18 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tremors with similar medicines

Tremors after Gabapentin 536 reports · 5.9% of its reports
Tremors after Selegiline (Anipryl) 127 reports · 3.1% of its reports
Tremors after Trazodone 167 reports · 6.6% of its reports
Tremors after Clomipramine (Clomicalm) 91 reports · 6.0% of its reports

All reported side effects of Fluoxetine in dogs · Medicines most reported with tremors