Tremors after Clomipramine (Clomicalm) in dogs

91 reports to the FDA describe tremors in dogs given Clomipramine. That is 6.0% of all reports for this medicine, compared with 3.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

91Reports

12%Marked serious

13%Recovered

4.4%Died or euthanised

6 daysTypical onset

How soon it started

Same day

3 23%

1–2 days

2 15%

3–7 days

3 23%

1–4 weeks

1 7.7%

Over a month

4 31%

How the animals did

Recovered

11 12%

Recovered with lasting effects

1 1.1%

Still unwell when reported

4 4.4%

Died

4 4.4%

Not known

71 78%

Problems reported at the same time

25 27%

20 22%

18 20%

14 15%

14 15%

13 14%

12 13%

12 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Clomipramine treats separation anxiety.

Products with this ingredient include Clomicalm. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Clomipramine cause tremors in dogs?: 91 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 6 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tremors with similar medicines

Tremors after Gabapentin 536 reports · 5.9% of its reports
Tremors after Selegiline (Anipryl) 127 reports · 3.1% of its reports
Tremors after Fluoxetine 244 reports · 9.4% of its reports
Tremors after Trazodone 167 reports · 6.6% of its reports

All reported side effects of Clomipramine in dogs · Medicines most reported with tremors