Tachycardia after Clomipramine (Clomicalm) in dogs

The FDA has received 40 reports of tachycardia in dogs after Clomipramine. That is 2.6% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

40Reports

20%Marked serious

7.5%Recovered

13%Died or euthanised

–Typical onset

How the animals did

Recovered

2 5.0%

Recovered with lasting effects

1 2.5%

Still unwell when reported

1 2.5%

Died

4 10%

Euthanised

1 2.5%

Not known

31 78%

Problems reported at the same time

19 48%

14 35%

13 33%

12 30%

8 20%

8 20%

Restlessness or agitation

8 20%

Diarrhea

7 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Clomipramine treats separation anxiety.

Products with this ingredient include Clomicalm. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Clomipramine cause tachycardia in dogs?: 40 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tachycardia with similar medicines

Tachycardia after Gabapentin 148 reports · 1.6% of its reports
Tachycardia after Selegiline (Anipryl) 28 reports · 0.7% of its reports
Tachycardia after Fluoxetine 28 reports · 1.1% of its reports
Tachycardia after Trazodone 51 reports · 2.0% of its reports

All reported side effects of Clomipramine in dogs · Medicines most reported with tachycardia