Tachycardia after Fluoxetine in dogs

The FDA has received 28 reports of tachycardia in dogs after Fluoxetine. That is 1.1% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

28Reports

36%Marked serious

25%Recovered

14%Died or euthanised

72 daysTypical onset

How soon it started

Same day

5 31%

1–2 days

1 6.3%

3–7 days

0 0.0%

1–4 weeks

1 6.3%

Over a month

9 56%

How the animals did

Recovered

6 21%

Recovered with lasting effects

1 3.6%

Still unwell when reported

3 11%

Died

3 11%

Euthanised

1 3.6%

Not known

14 50%

Problems reported at the same time

11 39%

10 36%

10 36%

9 32%

8 29%

7 25%

Eye or vision problems

6 21%

Vocalising

5 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Fluoxetine treats anxiety and behaviour problems.

Questions owners ask

Can Fluoxetine cause tachycardia in dogs?: 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 72 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tachycardia with similar medicines

Tachycardia after Gabapentin 148 reports · 1.6% of its reports
Tachycardia after Selegiline (Anipryl) 28 reports · 0.7% of its reports
Tachycardia after Trazodone 51 reports · 2.0% of its reports
Tachycardia after Clomipramine (Clomicalm) 40 reports · 2.6% of its reports

All reported side effects of Fluoxetine in dogs · Medicines most reported with tachycardia