Fluoxetine side effects in dogs

2,583 reports sent to the FDA between 2004 and 2026 involve Fluoxetine in dogs. The most reported problems were loss of appetite, vomiting, lethargy. 23% were marked serious, and where it was recorded, signs eased after stopping the medicine in 59% of cases.

2,583Reports
23%Marked serious
48%Only medicine involved
24%Recovered
4.3%Died or euthanised
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About this medicine

Fluoxetine treats anxiety and behaviour problems.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop fleas
11 0.4%
Didn't stop ticks
4 0.2%

How soon problems started

Same day
246 21%
1–2 days
114 9.7%
3–7 days
78 6.6%
1–4 weeks
175 15%
Over a month
562 48%

Time from the first dose to the first sign, where both dates were reported (1,175 reports).

How the animals did

Recovered
526 20%
Recovered with lasting effects
97 3.8%
Still unwell when reported
432 17%
Died
55 2.1%
Euthanised
56 2.2%
Not known
1,417 55%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other behaviour or anxiety medicines for dogs