Kidney problems after Trazodone in dogs

The FDA has received 161 reports of kidney problems in dogs after Trazodone. That is 6.4% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

161Reports

76%Marked serious

9.3%Recovered

34%Died or euthanised

17 daysTypical onset

How soon it started

Same day

11 9.2%

1–2 days

18 15%

3–7 days

21 18%

1–4 weeks

26 22%

Over a month

43 36%

How the animals did

Recovered

15 9.3%

Still unwell when reported

60 37%

Died

17 11%

Euthanised

37 23%

Not known

32 20%

Problems reported at the same time

90 56%

76 47%

66 41%

64 40%

54 34%

40 25%

33 20%

31 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause kidney problems in dogs?: 161 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 17 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Gabapentin 801 reports · 8.9% of its reports
Kidney problems after Selegiline (Anipryl) 158 reports · 3.8% of its reports
Kidney problems after Fluoxetine 58 reports · 2.2% of its reports
Kidney problems after Clomipramine (Clomicalm) 60 reports · 4.0% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with kidney problems