Kidney problems after Fluoxetine in dogs

58 reports to the FDA describe kidney problems in dogs given Fluoxetine. That is 2.2% of all reports for this medicine, compared with 2.4% across reports for all dog medicines.

58Reports

55%Marked serious

8.6%Recovered

26%Died or euthanised

101 daysTypical onset

How soon it started

Same day

1 2.7%

1–2 days

2 5.4%

3–7 days

4 11%

1–4 weeks

4 11%

Over a month

26 70%

How the animals did

Recovered

4 6.9%

Recovered with lasting effects

1 1.7%

Still unwell when reported

23 40%

Died

6 10%

Euthanised

9 16%

Not known

15 26%

Problems reported at the same time

27 47%

27 47%

19 33%

15 26%

15 26%

Hyperglycaemia

9 16%

Blood problems

9 16%

Diarrhea

9 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Fluoxetine treats anxiety and behaviour problems.

Questions owners ask

Can Fluoxetine cause kidney problems in dogs?: 58 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 101 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Gabapentin 801 reports · 8.9% of its reports
Kidney problems after Selegiline (Anipryl) 158 reports · 3.8% of its reports
Kidney problems after Trazodone 161 reports · 6.4% of its reports
Kidney problems after Clomipramine (Clomicalm) 60 reports · 4.0% of its reports

All reported side effects of Fluoxetine in dogs · Medicines most reported with kidney problems