Blood problems after Fluoxetine in dogs

The FDA has received 41 reports of blood problems in dogs after Fluoxetine. That is 1.6% of all reports for this medicine, compared with 1.8% across reports for all dog medicines.

41Reports

63%Marked serious

17%Recovered

20%Died or euthanised

30 daysTypical onset

How soon it started

Same day

1 3.4%

1–2 days

3 10%

3–7 days

4 14%

1–4 weeks

7 24%

Over a month

14 48%

How the animals did

Recovered

5 12%

Recovered with lasting effects

2 4.9%

Still unwell when reported

21 51%

Died

2 4.9%

Euthanised

6 15%

Not known

5 12%

Problems reported at the same time

19 46%

16 39%

15 37%

15 37%

9 22%

8 20%

7 17%

7 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Fluoxetine treats anxiety and behaviour problems.

Questions owners ask

Can Fluoxetine cause blood problems in dogs?: 41 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 30 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood problems with similar medicines

Blood problems after Gabapentin 460 reports · 5.1% of its reports
Blood problems after Selegiline (Anipryl) 101 reports · 2.5% of its reports
Blood problems after Trazodone 103 reports · 4.1% of its reports
Blood problems after Clomipramine (Clomicalm) 34 reports · 2.2% of its reports

All reported side effects of Fluoxetine in dogs · Medicines most reported with blood problems