Nausea after Selamectin (Revolution) in dogs

56 reports to the FDA describe nausea in dogs given Selamectin. That is 0.2% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

56Reports

20%Marked serious

14%Recovered

0.0%Died or euthanised

1 daysTypical onset

How soon it started

Same day

10 32%

1–2 days

11 35%

3–7 days

7 23%

1–4 weeks

2 6.5%

Over a month

1 3.2%

How the animals did

Recovered

8 14%

Still unwell when reported

19 34%

Not known

29 52%

Problems reported at the same time

28 50%

26 46%

16 29%

12 21%

8 14%

6 11%

5 8.9%

5 8.9%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Selamectin prevents heartworm and treats fleas, ear mites and some worms (spot-on).

Products with this ingredient include Revolution. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Selamectin cause nausea in dogs?: 56 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Nausea with similar medicines

Nausea after Ivermectin + Pyrantel (Heartgard Plus) 233 reports · 0.2% of its reports
Nausea after Milbemycin Oxime + Spinosad (Trifexis) 876 reports · 0.7% of its reports
Nausea after Moxidectin (ProHeart 6) 146 reports · 0.3% of its reports
Nausea after Milbemycin Oxime + Praziquantel (Interceptor Plus) 126 reports · 0.4% of its reports
Nausea after Milbemycin Oxime (Interceptor) 65 reports · 0.2% of its reports
Nausea after Ivermectin (Heartgard) 55 reports · 0.5% of its reports
Nausea after Ivermectin + Praziquantel + Pyrantel (Iverhart Max) 26 reports · 0.3% of its reports

All reported side effects of Selamectin in dogs · Medicines most reported with nausea