Loss of appetite after S-adenosylmethionine in dogs

89 reports to the FDA describe loss of appetite in dogs given S-adenosylmethionine. That is 23% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

89Reports
63%Marked serious
25%Recovered
25%Died or euthanised
28 daysTypical onset
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How soon it started

Same day
9 14%
1–2 days
7 11%
3–7 days
7 11%
1–4 weeks
12 18%
Over a month
31 47%

How the animals did

Recovered
19 21%
Recovered with lasting effects
3 3.4%
Still unwell when reported
31 35%
Died
7 7.9%
Euthanised
15 17%
Not known
14 16%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
2
4–7 years
12
8–11 years
32
12+ years
40

About this medicine

Type: medicine.

Questions owners ask

Can S-adenosylmethionine cause loss of appetite in dogs?
89 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 28 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of S-adenosylmethionine in dogs · Medicines most reported with loss of appetite