Vomiting after S-adenosylmethionine in dogs

The FDA has received 148 reports of vomiting in dogs after S-adenosylmethionine. That is 38% of all reports for this medicine, compared with 28% across reports for all dog medicines.

148Reports
34%Marked serious
55%Recovered
13%Died or euthanised
52 daysTypical onset
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How soon it started

Same day
11 11%
1–2 days
7 7.3%
3–7 days
11 11%
1–4 weeks
12 13%
Over a month
55 57%

How the animals did

Recovered
78 53%
Recovered with lasting effects
4 2.7%
Still unwell when reported
30 20%
Died
7 4.7%
Euthanised
12 8.1%
Not known
17 11%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
16
4–7 years
28
8–11 years
45
12+ years
55

About this medicine

Type: medicine.

Questions owners ask

Can S-adenosylmethionine cause vomiting in dogs?
148 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 52 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

All reported side effects of S-adenosylmethionine in dogs · Medicines most reported with vomiting