Licking after Pyrantel + Sarolaner (Simparica Trio) in dogs

76 reports to the FDA describe licking in dogs given Pyrantel + Sarolaner. That is 0.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

76Reports

46%Marked serious

17%Recovered

1.3%Died or euthanised

2 daysTypical onset

How soon it started

Same day

25 35%

1–2 days

12 17%

3–7 days

11 15%

1–4 weeks

10 14%

Over a month

13 18%

How the animals did

Recovered

13 17%

Still unwell when reported

33 43%

Euthanised

1 1.3%

Not known

29 38%

Problems reported at the same time

17 22%

14 18%

8 11%

8 11%

8 11%

Reddening of the skin

7 9.2%

Skin rash or irritation

7 9.2%

Hair loss

7 9.2%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms. Sarolaner kills fleas, ticks and some mites; monthly.

Products with this combination include Simparica Trio (which also contains moxidectin). The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Pyrantel + Sarolaner cause licking in dogs?: 76 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Licking with similar medicines

Licking after Febantel + Praziquantel + Pyrantel (Drontal Plus) 23 reports · 0.3% of its reports

All reported side effects of Pyrantel + Sarolaner in dogs · Medicines most reported with licking