Tremors after Prednisolone + Trimeprazine in dogs

109 reports to the FDA describe tremors in dogs given Prednisolone + Trimeprazine. That is 5.2% of all reports for this medicine, compared with 3.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

109Reports
28%Marked serious
33%Recovered
8.3%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
16 23%
1–2 days
10 14%
3–7 days
8 12%
1–4 weeks
14 20%
Over a month
21 30%

How the animals did

Recovered
30 28%
Recovered with lasting effects
6 5.5%
Still unwell when reported
29 27%
Died
4 3.7%
Euthanised
5 4.6%
Not known
35 32%

Problems reported at the same time

Age of the animals

Under 1 year
7
1–3 years
27
4–7 years
29
8–11 years
27
12+ years
16

About this medicine

Prednisolone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisolone + Trimeprazine cause tremors in dogs?
109 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tremors with similar medicines

All reported side effects of Prednisolone + Trimeprazine in dogs · Medicines most reported with tremors