Retching after Praziquantel + Pyrantel in dogs

36 reports to the FDA describe retching in dogs given Praziquantel + Pyrantel. That is 1.0% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

36Reports

36%Marked serious

31%Recovered

5.6%Died or euthanised

Same dayTypical onset

How soon it started

Same day

22 79%

1–2 days

6 21%

3–7 days

0 0.0%

1–4 weeks

0 0.0%

Over a month

0 0.0%

How the animals did

Recovered

11 31%

Died

2 5.6%

Not known

23 64%

Problems reported at the same time

19 53%

12 33%

10 28%

7 19%

3 8.3%

3 8.3%

3 8.3%

3 8.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause retching in dogs?: 36 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Retching with similar medicines

Retching after Pyrantel + Sarolaner (Simparica Trio) 77 reports · 0.1% of its reports
Retching after Febantel + Praziquantel + Pyrantel (Drontal Plus) 57 reports · 0.8% of its reports
Retching after Fenbendazole 80 reports · 1.4% of its reports
Retching after Pyrantel 50 reports · 1.0% of its reports

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with retching