Retching after Febantel + Praziquantel + Pyrantel (Drontal Plus) in dogs

57 reports to the FDA describe retching in dogs given Febantel + Praziquantel + Pyrantel. That is 0.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

57Reports
35%Marked serious
42%Recovered
8.8%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
32 63%
1–2 days
13 25%
3–7 days
3 5.9%
1–4 weeks
1 2.0%
Over a month
2 3.9%

How the animals did

Recovered
24 42%
Still unwell when reported
3 5.3%
Died
5 8.8%
Not known
25 44%

Problems reported at the same time

Vomiting
40 70%
Lethargy
14 25%
Loss of appetite
12 21%
Drooling
7 12%
Death
5 8.8%
Cough
5 8.8%
Tremors
5 8.8%
Behaviour change
5 8.8%

Age of the animals

Under 1 year
30
1–3 years
10
4–7 years
8
8–11 years
5
12+ years
2

About this medicine

Febantel treats intestinal worms. Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Products with this combination include Drontal Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Febantel + Praziquantel + Pyrantel cause retching in dogs?
57 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Retching with similar medicines

All reported side effects of Febantel + Praziquantel + Pyrantel in dogs · Medicines most reported with retching