Pale mucous membrane after Praziquantel + Pyrantel in dogs

35 reports to the FDA describe pale mucous membrane in dogs given Praziquantel + Pyrantel. That is 0.9% of all reports for this medicine, compared with 0.7% across reports for all dog medicines.

35Reports

77%Marked serious

26%Recovered

20%Died or euthanised

1 daysTypical onset

How soon it started

Same day

12 46%

1–2 days

6 23%

3–7 days

3 12%

1–4 weeks

1 3.8%

Over a month

4 15%

How the animals did

Recovered

9 26%

Still unwell when reported

5 14%

Died

4 11%

Euthanised

3 8.6%

Not known

14 40%

Problems reported at the same time

23 66%

22 63%

11 31%

11 31%

8 23%

7 20%

Hypothermia

6 17%

Liver problems

6 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause pale mucous membrane in dogs?: 35 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pale mucous membrane with similar medicines

Pale mucous membrane after Pyrantel + Sarolaner (Simparica Trio) 119 reports · 0.2% of its reports
Pale mucous membrane after Febantel + Praziquantel + Pyrantel (Drontal Plus) 35 reports · 0.5% of its reports
Pale mucous membrane after Fenbendazole 62 reports · 1.1% of its reports
Pale mucous membrane after Pyrantel 140 reports · 2.9% of its reports

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with pale mucous membrane