Inappropriate urination after Praziquantel + Pyrantel in dogs

25 reports to the FDA describe inappropriate urination in dogs given Praziquantel + Pyrantel. That is 0.7% of all reports for this medicine, compared with 0.5% across reports for all dog medicines.

25Reports

76%Marked serious

36%Recovered

20%Died or euthanised

1 daysTypical onset

How soon it started

Same day

10 43%

1–2 days

6 26%

3–7 days

2 8.7%

1–4 weeks

2 8.7%

Over a month

3 13%

How the animals did

Recovered

8 32%

Recovered with lasting effects

1 4.0%

Died

3 12%

Euthanised

2 8.0%

Not known

11 44%

Problems reported at the same time

8 32%

7 28%

7 28%

6 24%

5 20%

5 20%

5 20%

4 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause inappropriate urination in dogs?: 25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Inappropriate urination with similar medicines

Inappropriate urination after Pyrantel + Sarolaner (Simparica Trio) 247 reports · 0.5% of its reports
Inappropriate urination after Febantel + Praziquantel + Pyrantel (Drontal Plus) 31 reports · 0.5% of its reports
Inappropriate urination after Fenbendazole 25 reports · 0.4% of its reports
Inappropriate urination after Pyrantel 22 reports · 0.5% of its reports

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with inappropriate urination