Didn't work as expected after Praziquantel + Pyrantel in dogs

118 reports to the FDA describe didn't work as expected in dogs given Praziquantel + Pyrantel. That is 3.2% of all reports for this medicine, compared with 13% across reports for all dog medicines, so it is reported less often than average with this medicine.

118Reports
19%Marked serious
5.9%Recovered
2.5%Died or euthanised
21 daysTypical onset
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How soon it started

Same day
14 18%
1–2 days
4 5.1%
3–7 days
6 7.6%
1–4 weeks
31 39%
Over a month
24 30%

How the animals did

Recovered
7 5.9%
Still unwell when reported
21 18%
Died
3 2.5%
Not known
87 74%

Problems reported at the same time

19 16%
12 10%
8 6.8%
Drug dose administration interval too long
8 6.8%

Age of the animals

Under 1 year
36
1–3 years
38
4–7 years
20
8–11 years
6
12+ years
1

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause didn't work as expected in dogs?
118 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 21 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with didn't work as expected