Didn't stop worms after Praziquantel + Pyrantel in dogs

327 reports to the FDA describe didn't stop worms in dogs given Praziquantel + Pyrantel. That is 8.9% of all reports for this medicine, compared with 8.4% across reports for all dog medicines.

327Reports

25%Marked serious

5.8%Recovered

1.5%Died or euthanised

21 daysTypical onset

How soon it started

Same day

53 20%

1–2 days

21 8.1%

3–7 days

28 11%

1–4 weeks

51 20%

Over a month

106 41%

How the animals did

Recovered

19 5.8%

Still unwell when reported

61 19%

Died

5 1.5%

Not known

242 74%

Problems reported at the same time

Vomiting

47 14%

Diarrhea

41 13%

Didn't work as expected

29 8.9%

Lethargy

28 8.6%

Loss of appetite

19 5.8%

Drug administration error

17 5.2%

Loose stool

13 4.0%

Vocalising

9 2.8%

Age of the animals

Under 1 year

133

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause didn't stop worms in dogs?: 327 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 21 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't stop worms with similar medicines

Didn't stop worms after Pyrantel + Sarolaner (Simparica Trio) 10,714 reports · 20% of its reports
Didn't stop worms after Febantel + Praziquantel + Pyrantel (Drontal Plus) 1,252 reports · 19% of its reports
Didn't stop worms after Fenbendazole 1,224 reports · 21% of its reports
Didn't stop worms after Pyrantel 808 reports · 17% of its reports
Didn't stop worms after Praziquantel 403 reports · 36% of its reports

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with didn't stop worms