Urinary tract infection after Polysulfated Glycosaminoglycan in dogs

The FDA has received 67 reports of urinary tract infection in dogs after Polysulfated Glycosaminoglycan. That is 1.2% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

67Reports

72%Marked serious

19%Recovered

12%Died or euthanised

31 daysTypical onset

How soon it started

Same day

5 13%

1–2 days

0 0.0%

3–7 days

6 15%

1–4 weeks

8 21%

Over a month

20 51%

How the animals did

Recovered

11 16%

Recovered with lasting effects

2 3.0%

Still unwell when reported

28 42%

Died

3 4.5%

Euthanised

5 7.5%

Not known

18 27%

Problems reported at the same time

20 30%

18 27%

14 21%

14 21%

13 19%

12 18%

Didn't work as expected

11 16%

Lethargy

11 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause urinary tract infection in dogs?: 67 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 31 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Urinary tract infection with similar medicines

Urinary tract infection after Melarsomine (Immiticide) 45 reports · 0.2% of its reports
Urinary tract infection after Diphenhydramine 42 reports · 0.9% of its reports
Urinary tract infection after Butorphanol 30 reports · 0.7% of its reports
Urinary tract infection after Cefpodoxime 89 reports · 2.2% of its reports
Urinary tract infection after Tramadol 74 reports · 2.0% of its reports
Urinary tract infection after Desoxycorticosterone Pivalate 93 reports · 2.8% of its reports
Urinary tract infection after Dirlotapide 22 reports · 0.8% of its reports
Urinary tract infection after Cephalexin 30 reports · 1.1% of its reports
Urinary tract infection after Famotidine 54 reports · 2.0% of its reports
Urinary tract infection after Chondroitin + Glucosamine 47 reports · 1.8% of its reports

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with urinary tract infection