Unable to stand after Polysulfated Glycosaminoglycan in dogs

The FDA has received 48 reports of unable to stand in dogs after Polysulfated Glycosaminoglycan. That is 0.9% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

48Reports
79%Marked serious
25%Recovered
40%Died or euthanised
24 daysTypical onset
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How soon it started

Same day
10 25%
1–2 days
3 7.5%
3–7 days
1 2.5%
1–4 weeks
8 20%
Over a month
18 45%

How the animals did

Recovered
12 25%
Still unwell when reported
9 19%
Died
3 6.3%
Euthanised
16 33%
Not known
8 17%

Problems reported at the same time

Death
19 40%
Lethargy
16 33%
Weakness
16 33%
Loss of appetite
15 31%
Vomiting
11 23%
Breathing problems
10 21%
Liver problems
10 21%
Diarrhea
9 19%

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
5
8–11 years
14
12+ years
28

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause unable to stand in dogs?
48 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 24 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Unable to stand with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with unable to stand