Splenic neoplasm after Polysulfated Glycosaminoglycan in dogs

20 reports to the FDA describe splenic neoplasm in dogs given Polysulfated Glycosaminoglycan. That is 0.4% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

20Reports

75%Marked serious

15%Recovered

55%Died or euthanised

–Typical onset

How the animals did

Recovered

3 15%

Still unwell when reported

3 15%

Died

4 20%

Euthanised

7 35%

Not known

3 15%

Problems reported at the same time

12 60%

11 55%

8 40%

7 35%

Abnormal ultrasound finding

6 30%

Blood problems

6 30%

Abnormal radiograph finding

3 15%

Leucocytosis

3 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause splenic neoplasm in dogs?: 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with splenic neoplasm