Sleepiness - systemic disorder after Polysulfated Glycosaminoglycan in dogs

The FDA has received 27 reports of sleepiness - systemic disorder in dogs after Polysulfated Glycosaminoglycan. That is 0.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

27Reports

56%Marked serious

33%Recovered

19%Died or euthanised

Same dayTypical onset

How soon it started

Same day

13 59%

1–2 days

2 9.1%

3–7 days

1 4.5%

1–4 weeks

3 14%

Over a month

3 14%

How the animals did

Recovered

9 33%

Still unwell when reported

4 15%

Euthanised

5 19%

Not known

9 33%

Problems reported at the same time

11 41%

6 22%

6 22%

6 22%

5 19%

5 19%

5 19%

5 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause sleepiness - systemic disorder in dogs?: 27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Sleepiness - systemic disorder with similar medicines

Sleepiness - systemic disorder after Diphenhydramine 27 reports · 0.6% of its reports
Sleepiness - systemic disorder after Butorphanol 23 reports · 0.5% of its reports

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with sleepiness - systemic disorder