Pancreatitis after Polysulfated Glycosaminoglycan in dogs

The FDA has received 48 reports of pancreatitis in dogs after Polysulfated Glycosaminoglycan. That is 0.9% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

48Reports
83%Marked serious
31%Recovered
21%Died or euthanised
19 daysTypical onset
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How soon it started

Same day
6 21%
1–2 days
4 14%
3–7 days
1 3.4%
1–4 weeks
7 24%
Over a month
11 38%

How the animals did

Recovered
14 29%
Recovered with lasting effects
1 2.1%
Still unwell when reported
11 23%
Died
3 6.3%
Euthanised
7 15%
Not known
12 25%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
9
8–11 years
22
12+ years
16

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause pancreatitis in dogs?
48 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 19 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pancreatitis with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with pancreatitis