Pancreatitis after Melarsomine (Immiticide) in dogs

The FDA has received 41 reports of pancreatitis in dogs after Melarsomine. That is 0.2% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

41Reports

66%Marked serious

15%Recovered

20%Died or euthanised

22 daysTypical onset

How soon it started

Same day

3 11%

1–2 days

1 3.6%

3–7 days

6 21%

1–4 weeks

6 21%

Over a month

12 43%

How the animals did

Recovered

6 15%

Still unwell when reported

9 22%

Died

3 7.3%

Euthanised

5 12%

Not known

18 44%

Problems reported at the same time

23 56%

20 49%

14 34%

12 29%

12 29%

11 27%

9 22%

8 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause pancreatitis in dogs?: 41 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 22 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pancreatitis with similar medicines

Pancreatitis after Polysulfated Glycosaminoglycan 48 reports · 0.9% of its reports
Pancreatitis after Diphenhydramine 29 reports · 0.6% of its reports
Pancreatitis after Butorphanol 40 reports · 0.9% of its reports
Pancreatitis after Cefpodoxime 35 reports · 0.9% of its reports
Pancreatitis after Tramadol 41 reports · 1.1% of its reports
Pancreatitis after Desoxycorticosterone Pivalate 34 reports · 1.0% of its reports
Pancreatitis after Propofol 23 reports · 0.7% of its reports
Pancreatitis after Isoflurane 20 reports · 0.7% of its reports
Pancreatitis after Famotidine 75 reports · 2.8% of its reports
Pancreatitis after Chondroitin + Glucosamine 33 reports · 1.3% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with pancreatitis