Inappropriate urination after Phenylpropanolamine (Proin) in dogs
The FDA has received 40 reports of inappropriate urination in dogs after Phenylpropanolamine. That is 1.0% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.
40Reports
55%Marked serious
28%Recovered
10%Died or euthanised
22 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Phenylpropanolamine treats urinary incontinence.
Products with this ingredient include Proin. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Phenylpropanolamine cause inappropriate urination in dogs?
- 40 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 22 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Inappropriate urination with similar medicines
- Inappropriate urination after Trilostane (Vetoryl) 405 reports · 3.4% of its reports
- Inappropriate urination after Insulin 67 reports · 0.9% of its reports
- Inappropriate urination after Levothyroxine 50 reports · 1.7% of its reports
All reported side effects of Phenylpropanolamine in dogs · Medicines most reported with inappropriate urination