Drug administration error after Phenylpropanolamine (Proin) in dogs

50 reports to the FDA describe drug administration error in dogs given Phenylpropanolamine. That is 1.2% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

50Reports
22%Marked serious
38%Recovered
4.0%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
12 50%
1–2 days
5 21%
3–7 days
2 8.3%
1–4 weeks
2 8.3%
Over a month
3 13%

How the animals did

Recovered
19 38%
Still unwell when reported
3 6.0%
Died
1 2.0%
Euthanised
1 2.0%
Not known
26 52%

Problems reported at the same time

Age of the animals

Under 1 year
3
1–3 years
6
4–7 years
6
8–11 years
16
12+ years
19

About this medicine

Phenylpropanolamine treats urinary incontinence.

Products with this ingredient include Proin. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Phenylpropanolamine cause drug administration error in dogs?
50 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Drug administration error with similar medicines

All reported side effects of Phenylpropanolamine in dogs · Medicines most reported with drug administration error