Neutrophilia after Midazolam in dogs

The FDA has received 53 reports of neutrophilia in dogs after Midazolam. That is 4.4% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

53Reports
94%Marked serious
9.4%Recovered
34%Died or euthanised
3 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
5 10%
1–2 days
17 35%
3–7 days
10 21%
1–4 weeks
6 13%
Over a month
10 21%

How the animals did

Recovered
4 7.5%
Recovered with lasting effects
1 1.9%
Still unwell when reported
22 42%
Died
4 7.5%
Euthanised
14 26%
Not known
8 15%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
9
4–7 years
9
8–11 years
21
12+ years
6

About this medicine

Type: medicine.

Questions owners ask

Can Midazolam cause neutrophilia in dogs?
53 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutrophilia with similar medicines

All reported side effects of Midazolam in dogs · Medicines most reported with neutrophilia