Lethargy after Midazolam in dogs

The FDA has received 212 reports of lethargy in dogs after Midazolam. That is 18% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

212Reports
81%Marked serious
17%Recovered
33%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
47 24%
1–2 days
59 31%
3–7 days
34 18%
1–4 weeks
28 15%
Over a month
24 13%

How the animals did

Recovered
37 17%
Still unwell when reported
84 40%
Died
28 13%
Euthanised
43 20%
Not known
20 9.4%

Problems reported at the same time

Age of the animals

Under 1 year
18
1–3 years
47
4–7 years
49
8–11 years
71
12+ years
26

About this medicine

Type: medicine.

Questions owners ask

Can Midazolam cause lethargy in dogs?
212 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Midazolam in dogs · Medicines most reported with lethargy