Seizures after Midazolam in dogs

The FDA has received 248 reports of seizures in dogs after Midazolam. That is 21% of all reports for this medicine, compared with 4.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

248Reports
98%Marked serious
23%Recovered
44%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
105 45%
1–2 days
48 21%
3–7 days
28 12%
1–4 weeks
25 11%
Over a month
26 11%

How the animals did

Recovered
56 23%
Recovered with lasting effects
1 0.4%
Still unwell when reported
62 25%
Died
54 22%
Euthanised
54 22%
Not known
21 8.5%

Problems reported at the same time

Age of the animals

Under 1 year
24
1–3 years
58
4–7 years
52
8–11 years
67
12+ years
40

About this medicine

Type: medicine.

Questions owners ask

Can Midazolam cause seizures in dogs?
248 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

All reported side effects of Midazolam in dogs · Medicines most reported with seizures