Kidney problems after Midazolam in dogs

The FDA has received 102 reports of kidney problems in dogs after Midazolam. That is 8.5% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

102Reports
95%Marked serious
8.8%Recovered
45%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
17 18%
1–2 days
23 25%
3–7 days
16 17%
1–4 weeks
17 18%
Over a month
19 21%

How the animals did

Recovered
9 8.8%
Still unwell when reported
34 33%
Died
15 15%
Euthanised
31 30%
Not known
13 13%

Problems reported at the same time

Age of the animals

Under 1 year
13
1–3 years
17
4–7 years
28
8–11 years
28
12+ years
16

About this medicine

Type: medicine.

Questions owners ask

Can Midazolam cause kidney problems in dogs?
102 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

All reported side effects of Midazolam in dogs · Medicines most reported with kidney problems