Skin rash or irritation after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) in dogs
45 reports to the FDA describe skin rash or irritation in dogs given Lufenuron + Milbemycin Oxime + Praziquantel. That is 0.5% of all reports for this medicine, compared with 1.3% across reports for all dog medicines, so it is reported less often than average with this medicine.
45Reports
67%Marked serious
24%Recovered
0.0%Died or euthanised
2 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Lufenuron stops flea eggs from developing. Milbemycin Oxime prevents heartworm and controls some intestinal worms (monthly). Praziquantel treats tapeworms.
Products with this combination include Sentinel Spectrum. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Lufenuron + Milbemycin Oxime + Praziquantel cause skin rash or irritation in dogs?
- 45 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 2 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Skin rash or irritation with similar medicines
- Skin rash or irritation after Spinosad (Comfortis) 726 reports · 1.3% of its reports
- Skin rash or irritation after Lufenuron + Milbemycin Oxime (Sentinel) 344 reports · 1.3% of its reports
- Skin rash or irritation after Imidacloprid + Moxidectin (Advantage Multi) 504 reports · 3.8% of its reports
- Skin rash or irritation after Nitenpyram (Capstar) 163 reports · 1.5% of its reports
- Skin rash or irritation after Fipronil + S-methoprene (Frontline Plus) 62 reports · 2.1% of its reports
- Skin rash or irritation after Flumethrin + Imidacloprid (Seresto) 103 reports · 4.5% of its reports
- Skin rash or irritation after Imidacloprid 44 reports · 2.3% of its reports
- Skin rash or irritation after Fipronil 30 reports · 2.1% of its reports
- Skin rash or irritation after Lufenuron 60 reports · 5.9% of its reports
- Skin rash or irritation after Imidacloprid + Permethrin + Pyriproxyfen 25 reports · 3.4% of its reports
All reported side effects of Lufenuron + Milbemycin Oxime + Praziquantel in dogs · Medicines most reported with skin rash or irritation