Skin rash or irritation after Lufenuron in dogs

The FDA has received 60 reports of skin rash or irritation in dogs after Lufenuron. That is 5.9% of all reports for this medicine, compared with 1.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

60Reports

3.3%Marked serious

1.7%Recovered

3.3%Died or euthanised

–Typical onset

How the animals did

Recovered

1 1.7%

Still unwell when reported

2 3.3%

Died

2 3.3%

Not known

55 92%

Problems reported at the same time

25 42%

10 17%

7 12%

7 12%

6 10%

Pyoderma

5 8.3%

Lethargy

4 6.7%

Loss of appetite

4 6.7%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lufenuron stops flea eggs from developing.

Questions owners ask

Can Lufenuron cause skin rash or irritation in dogs?: 60 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin rash or irritation with similar medicines

Skin rash or irritation after Spinosad (Comfortis) 726 reports · 1.3% of its reports
Skin rash or irritation after Lufenuron + Milbemycin Oxime (Sentinel) 344 reports · 1.3% of its reports
Skin rash or irritation after Imidacloprid + Moxidectin (Advantage Multi) 504 reports · 3.8% of its reports
Skin rash or irritation after Nitenpyram (Capstar) 163 reports · 1.5% of its reports
Skin rash or irritation after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 45 reports · 0.5% of its reports
Skin rash or irritation after Fipronil + S-methoprene (Frontline Plus) 62 reports · 2.1% of its reports
Skin rash or irritation after Flumethrin + Imidacloprid (Seresto) 103 reports · 4.5% of its reports
Skin rash or irritation after Imidacloprid 44 reports · 2.3% of its reports
Skin rash or irritation after Fipronil 30 reports · 2.1% of its reports
Skin rash or irritation after Imidacloprid + Permethrin + Pyriproxyfen 25 reports · 3.4% of its reports

All reported side effects of Lufenuron in dogs · Medicines most reported with skin rash or irritation