Lufenuron side effects in dogs
1,018 reports sent to the FDA between 1995 and 2026 involve Lufenuron in dogs. The most reported problems were vomiting, lethargy, diarrhea. 2.7% were marked serious, and where it was recorded, signs eased after stopping the medicine in 14% of cases.
1,018Reports
2.7%Marked serious
94%Only medicine involved
2.8%Recovered
7.2%Died or euthanised
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About this medicine
Lufenuron stops flea eggs from developing.
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (49 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Labrador Retriever 74 reports
- Golden Retriever 43 reports
- Cocker American Spaniel 41 reports
- Poodle 38 reports
- Yorkshire Terrier 36 reports
- Schnauzer 32 reports
- Shih Tzu 28 reports
- Beagle 26 reports
- Dachshund 26 reports
- German Shepherd Dog 21 reports
Other flea and tick treatments for dogs
Spinosad (Comfortis)57,095 reports · 7.7% seriousLufenuron + Milbemycin Oxime (Sentinel)26,051 reports · 24% seriousImidacloprid + Moxidectin (Advantage Multi)13,117 reports · 57% seriousNitenpyram (Capstar)10,782 reports · 10.0% seriousLufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum)9,966 reports · 40% seriousFipronil + S-methoprene (Frontline Plus)2,954 reports · 49% seriousFlumethrin + Imidacloprid (Seresto)2,273 reports · 25% seriousImidacloprid1,908 reports · 11% serious