Skin hyperaemia after Lufenuron in dogs

The FDA has received 56 reports of skin hyperaemia in dogs after Lufenuron. That is 5.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

56Reports

0.0%Marked serious

0.0%Recovered

1.8%Died or euthanised

–Typical onset

How the animals did

Died

1 1.8%

Not known

55 98%

Problems reported at the same time

34 61%

9 16%

8 14%

8 14%

Skin rash or irritation

7 13%

Lethargy

6 11%

Vomiting

6 11%

Loss of appetite

4 7.1%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lufenuron stops flea eggs from developing.

Questions owners ask

Can Lufenuron cause skin hyperaemia in dogs?: 56 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin hyperaemia with similar medicines

Skin hyperaemia after Spinosad (Comfortis) 257 reports · 0.5% of its reports
Skin hyperaemia after Lufenuron + Milbemycin Oxime (Sentinel) 80 reports · 0.3% of its reports
Skin hyperaemia after Imidacloprid + Moxidectin (Advantage Multi) 31 reports · 0.2% of its reports
Skin hyperaemia after Nitenpyram (Capstar) 41 reports · 0.4% of its reports

All reported side effects of Lufenuron in dogs · Medicines most reported with skin hyperaemia