Skin hyperaemia after Imidacloprid + Moxidectin (Advantage Multi) in dogs
31 reports to the FDA describe skin hyperaemia in dogs given Imidacloprid + Moxidectin. That is 0.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.
31Reports
3.2%Marked serious
0.0%Recovered
0.0%Died or euthanised
–Typical onset
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How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Imidacloprid kills fleas (spot-on or collar). Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).
Products with this combination include Advantage Multi. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Imidacloprid + Moxidectin cause skin hyperaemia in dogs?
- 31 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Skin hyperaemia with similar medicines
- Skin hyperaemia after Spinosad (Comfortis) 257 reports · 0.5% of its reports
- Skin hyperaemia after Lufenuron + Milbemycin Oxime (Sentinel) 80 reports · 0.3% of its reports
- Skin hyperaemia after Nitenpyram (Capstar) 41 reports · 0.4% of its reports
- Skin hyperaemia after Lufenuron 56 reports · 5.5% of its reports
All reported side effects of Imidacloprid + Moxidectin in dogs · Medicines most reported with skin hyperaemia