Skin rash or irritation after Imidacloprid in dogs

44 reports to the FDA describe skin rash or irritation in dogs given Imidacloprid. That is 2.3% of all reports for this medicine, compared with 1.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

44Reports

23%Marked serious

14%Recovered

2.3%Died or euthanised

1 daysTypical onset

How soon it started

Same day

6 17%

1–2 days

18 51%

3–7 days

2 5.7%

1–4 weeks

2 5.7%

Over a month

7 20%

How the animals did

Recovered

5 11%

Recovered with lasting effects

1 2.3%

Still unwell when reported

6 14%

Euthanised

1 2.3%

Not known

31 70%

Problems reported at the same time

Didn't stop fleas

24 55%

Itching

19 43%

Hair loss

7 16%

Dry skin

6 14%

Lethargy

6 14%

Loss of appetite

6 14%

Diarrhea

5 11%

Adipsia

3 6.8%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Imidacloprid kills fleas (spot-on or collar).

Questions owners ask

Can Imidacloprid cause skin rash or irritation in dogs?: 44 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin rash or irritation with similar medicines

Skin rash or irritation after Spinosad (Comfortis) 726 reports · 1.3% of its reports
Skin rash or irritation after Lufenuron + Milbemycin Oxime (Sentinel) 344 reports · 1.3% of its reports
Skin rash or irritation after Imidacloprid + Moxidectin (Advantage Multi) 504 reports · 3.8% of its reports
Skin rash or irritation after Nitenpyram (Capstar) 163 reports · 1.5% of its reports
Skin rash or irritation after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 45 reports · 0.5% of its reports
Skin rash or irritation after Fipronil + S-methoprene (Frontline Plus) 62 reports · 2.1% of its reports
Skin rash or irritation after Flumethrin + Imidacloprid (Seresto) 103 reports · 4.5% of its reports
Skin rash or irritation after Fipronil 30 reports · 2.1% of its reports
Skin rash or irritation after Lufenuron 60 reports · 5.9% of its reports
Skin rash or irritation after Imidacloprid + Permethrin + Pyriproxyfen 25 reports · 3.4% of its reports

All reported side effects of Imidacloprid in dogs · Medicines most reported with skin rash or irritation