Drug dose omission after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) in dogs
233 reports to the FDA describe drug dose omission in dogs given Lufenuron + Milbemycin Oxime + Praziquantel. That is 2.3% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.
233Reports
61%Marked serious
6.4%Recovered
0.9%Died or euthanised
242 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Lufenuron stops flea eggs from developing. Milbemycin Oxime prevents heartworm and controls some intestinal worms (monthly). Praziquantel treats tapeworms.
Products with this combination include Sentinel Spectrum. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Lufenuron + Milbemycin Oxime + Praziquantel cause drug dose omission in dogs?
- 233 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 242 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Drug dose omission with similar medicines
- Drug dose omission after Spinosad (Comfortis) 498 reports · 0.9% of its reports
- Drug dose omission after Lufenuron + Milbemycin Oxime (Sentinel) 281 reports · 1.1% of its reports
- Drug dose omission after Imidacloprid + Moxidectin (Advantage Multi) 53 reports · 0.4% of its reports
All reported side effects of Lufenuron + Milbemycin Oxime + Praziquantel in dogs · Medicines most reported with drug dose omission