Increased respiratory rate after Leptospirosis Vaccine in dogs

55 reports to the FDA describe increased respiratory rate in dogs given Leptospirosis Vaccine. That is 0.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

55Reports
85%Marked serious
29%Recovered
35%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
23 47%
1–2 days
1 2.0%
3–7 days
2 4.1%
1–4 weeks
8 16%
Over a month
15 31%

How the animals did

Recovered
15 27%
Recovered with lasting effects
1 1.8%
Still unwell when reported
14 25%
Died
7 13%
Euthanised
12 22%
Not known
6 11%

Problems reported at the same time

Vomiting
33 60%
Lethargy
26 47%
Loss of appetite
23 42%
Breathing problems
22 40%
Allergic reaction
19 35%
Death
19 35%
Kidney problems
17 31%
Liver problems
16 29%

Age of the animals

Under 1 year
4
1–3 years
12
4–7 years
15
8–11 years
16
12+ years
7

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause increased respiratory rate in dogs?
55 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Increased respiratory rate with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with increased respiratory rate