Excessive thirst after Leptospirosis Vaccine in dogs

The FDA has received 159 reports of excessive thirst in dogs after Leptospirosis Vaccine. That is 2.0% of all reports for this medicine, compared with 1.4% across reports for all dog medicines.

159Reports

70%Marked serious

10%Recovered

21%Died or euthanised

6 daysTypical onset

How soon it started

Same day

29 24%

1–2 days

19 16%

3–7 days

16 13%

1–4 weeks

25 21%

Over a month

31 26%

How the animals did

Recovered

14 8.8%

Recovered with lasting effects

2 1.3%

Still unwell when reported

87 55%

Died

10 6.3%

Euthanised

23 14%

Not known

23 14%

Problems reported at the same time

90 57%

80 50%

66 42%

66 42%

56 35%

45 28%

33 21%

31 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause excessive thirst in dogs?: 159 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 6 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive thirst with similar medicines

Excessive thirst after Rabies Vaccine 143 reports · 1.4% of its reports
Excessive thirst after Bordetella Vaccine 147 reports · 1.6% of its reports
Excessive thirst after Lyme Vaccine 43 reports · 0.6% of its reports
Excessive thirst after Distemper-parvo Vaccine 94 reports · 1.5% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with excessive thirst