Excessive urination after Leptospirosis Vaccine in dogs

116 reports to the FDA describe excessive urination in dogs given Leptospirosis Vaccine. That is 1.4% of all reports for this medicine, compared with 1.0% across reports for all dog medicines.

116Reports
63%Marked serious
9.5%Recovered
17%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
23 26%
1–2 days
16 18%
3–7 days
12 14%
1–4 weeks
13 15%
Over a month
24 27%

How the animals did

Recovered
9 7.8%
Recovered with lasting effects
2 1.7%
Still unwell when reported
65 56%
Died
5 4.3%
Euthanised
15 13%
Not known
20 17%

Problems reported at the same time

Age of the animals

Under 1 year
16
1–3 years
16
4–7 years
21
8–11 years
40
12+ years
21

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause excessive urination in dogs?
116 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive urination with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with excessive urination