Proteinuria after Leptospirosis Vaccine in dogs

125 reports to the FDA describe proteinuria in dogs given Leptospirosis Vaccine. That is 1.6% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

125Reports
64%Marked serious
4.0%Recovered
27%Died or euthanised
17 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
19 24%
1–2 days
7 9.0%
3–7 days
7 9.0%
1–4 weeks
15 19%
Over a month
30 38%

How the animals did

Recovered
4 3.2%
Recovered with lasting effects
1 0.8%
Still unwell when reported
53 42%
Died
11 8.8%
Euthanised
23 18%
Not known
33 26%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
23
4–7 years
40
8–11 years
36
12+ years
18

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause proteinuria in dogs?
125 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 17 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Proteinuria with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with proteinuria