Eosinopenia after Leptospirosis Vaccine in dogs

60 reports to the FDA describe eosinopenia in dogs given Leptospirosis Vaccine. That is 0.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

60Reports

90%Marked serious

8.3%Recovered

38%Died or euthanised

20 daysTypical onset

How soon it started

Same day

13 25%

1–2 days

3 5.7%

3–7 days

8 15%

1–4 weeks

8 15%

Over a month

21 40%

How the animals did

Recovered

5 8.3%

Still unwell when reported

18 30%

Died

8 13%

Euthanised

15 25%

Not known

14 23%

Problems reported at the same time

39 65%

37 62%

36 60%

30 50%

29 48%

29 48%

28 47%

26 43%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause eosinopenia in dogs?: 60 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 20 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Eosinopenia with similar medicines

Eosinopenia after Rabies Vaccine 59 reports · 0.6% of its reports
Eosinopenia after Bordetella Vaccine 68 reports · 0.7% of its reports
Eosinopenia after Distemper-parvo Vaccine 46 reports · 0.7% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with eosinopenia